490 BioTech wins Innov865 Alliance’s Startup Day; Dr. Peter Tsai is Recognized for Global Pandemic Support

Innov865 Week Ends with a Virtual Celebration of Trailblazing Entrepreneurs and Life-changing Impact

KNOXVILLE, Tenn. — The startup 490 BioTech, which developed bioluminescent human cells to show changes in cellular health, won the Innov865 Judges’ Choice Award at Startup Day 2020 with a pitch that explained how its technology can improve development of pharmaceuticals.

“Healthy happy cells are bright, sick cells go dim, and dead cells go dark,” 490 BioTech co-founder and CEO Dan Close said. “Our product provides continuous information about a drug’s effect on human health so pharmaceutical companies can operate more efficiently.”

As winner, his company will receive a $7,000 cash prize that they will use to develop its business further. 490 BioTech was named among several winners during Innov865 Week, which celebrates entrepreneurship and innovation in Knoxville and the region. He and others pitched their businesses on Startup Day, Tuesday, Sept. 29.

Winners were named in an awards ceremony on Friday, Oct. 2 that included the judges’ choice, 490 BioTech; the Innov865 Crowd Favorite prize, presented by BB&T and SunTrust Bank, now Truist, was given to Quantum Lock; and the first recipient of the Innov865 Impact Award, presented by Verizon, was named – N95 mask developer Dr. Peter Tsai.

The look and feel of Innov865 Week may have been a little different, but the excitement of the eighth annual Startup Day was woven throughout the a week of virtual events designed to introduce investors to burgeoning startups in the process of gaining traction in the market.

The festivities started with a discussion from University of Tennessee President and entrepreneur Randy Boyd during a Facebook Live segment on Monday morning, followed by the Spark Innovation Center Showcase on Monday afternoon. On Tuesday nearly 200 attendees heard from Knoxville Mayor Indya Kincannon and then were introduced to six investable pitchers in what was deemed by judges as the closest Startup Day to date. The virtual “Shark Tank”-style pitch competition included previously taped pitches and virtual question and answer sessions hosted on the local startup virtual platform Lunchpool.

Quantum Lock, co-founded by Erica Grant, won the $3,000 Innov865 Crowd Favorite prize as voted on by viewers of the competition on Startup Day.

Quantum Lock creates random, untraceable combinations for locks that prevent hackers from doing things such as creating a master key for hotel rooms, among other safeguards. Later plans for Quantum Lock’s technology include securing the energy grid, hospitals, homes, smartphones and personal security.

“Encouraging entrepreneurs to creatively solve problems and build businesses is one way Truist delivers on its purpose of inspiring and building better lives and communities, said Christian Corts, regional president for BB&T | SunTrust now Truist, East Tennessee. “We appreciate the hard work and ingenuity of all of Startup Day’s participants, and congratulate Quantum Lock and Erica Grant as the crowd favorite award winner for Startup Day 2020.”

The inaugural Innov865 Impact Award, presented by Verizon, was given to Peter Tsai, University of Tennessee researcher who developed the N95 mask material.

“Verizon is proud to present the inaugural Innov865 Impact Award, and pleased to announce the winner, Peter Tsai,” said Thomas Green, Managing Partner for Government and Public Safety at Verizon. “As the architect behind the essential technology in N95 masks, his work is essential to the global response for fighting the pandemic. This is the kind of life-changing technology that the Innov865 Impact Award presented by Verizon is meant to highlight.

The Innov865 Impact Award recognizes an inventor who has made a positive impact in the fight against COVID-19. Tsai, a research faculty member at the University of Tennessee Department of Material Science and Engineering, used a method called electrostatic charging to develop the N95 mask material, which filters out 95 percent of particles from air that wearers breathe through the mask. Front-line healthcare workers and others use the N95 mask as part of the essential personal protective equipment they need during the COVID-19 pandemic.

Tsai then participated in a fireside chat with Lonnie Love of ORNL, moderated by Jon Sheiber with TechCrunch, in which he explained his work.

“I did not expect this. It’s just happened by chance,” Tsai said. “My invention is an ordinary invention.” However, Tsai’s invention has had an extraordinary impact. Dr. Tsai retired two years ago, but the global pandemic caused a shortage of N95 masks. Earlier this year, he worked with labs and manufacturers to teach others how to make the materials and safely reuse N95 masks.

About the Startup Day winners

Innov865 Judges Choice: 490 BioTech – The Knoxville-based 490 BioTech makes bioluminescent human cells capable of continuously producing a visual light signal that adjusts in real-time to represent changes in cellular health. The company’s glowing cells can be used by pharmaceutical companies in their efforts to develop safer, more effective, and less expensive medicines. 490 BioTech serves the academic, commercial, industrial, and government research community by providing high quality bioluminescent cell lines that don’t require external luciferin treatments to function.

Their patented genetic architecture allows their cell lines to produce their own luciferin internally, allowing for continuous light production throughout the life of a culture.

Cofounder and CSO: Dan Close

Innov865 Crowd Favorite prize, presented by BB&T and SunTrust Bank, now Truist: Quantum Lock Quantum Lock is developing a smart lock system that is more secure than many current smartphone-based key systems. Quantum Lock’s technology uses quantum physics to generate keys that are random and untraceable. Quantum Lock’s premier product, Gamma Lock, is a smart phone or key fob based smart lock which is built to secure guests at Bed and Breakfasts and hotels.

Cofounder: Erica Grant

About the Innov865 Alliance and Innov865 Week’s Startup Day

Innov865 Week is a weeklong series of events that celebrates Knoxville’s entrepreneurial spirit by bringing together startups, entrepreneurs, makers, investors, business leaders, students, and community leaders from across East Tennessee for a week of educational panels, pitch competitions, investor roundtables, and social events. It is presented by the Innov865 Alliance, a coalition that develops, supports, and promotes the region’s entrepreneurial ecosystem. Founding members of the Innov865 Alliance include the University of Tennessee Research Foundation, Oak Ridge National Laboratory, PYA, UT’s Anderson Center for Entrepreneurship and Innovation, Three Roots Capital, Tennessee Valley Authority, Launch Tennessee, Knoxville Entrepreneur Center, the University of Tennessee Research Park at Cherokee Farm, and Bunker Labs Knoxville. To learn more, visit https://innov865.com/.

Startup Day 2020 Awards Ceremony

Join us for the Startup Day 2020 Awards Ceremony! RSVP here.

About this Event

If you loved the excitement of Startup Day’s “Shark-Tank”-style pitch competition, you won’t want to miss the Startup Day 2020 Awards Ceremony!

During this end-of-the-week event, we will announce the winner of the Innov865 Judges’ Choice award, along with the Innov865 Crowd Favorite award, presented by BB&T and SunTrust Bank, now Truist.

A new addition to the Innov865 Week programming is the Innov865 Impact Award, presented by Verizon. The Innov865 Impact Award recognizes an inventor who has made a positive impact in the fight against COVID-19. The inaugural Innov865 Impact Award recipient will be announced and hold a fireside chat during the ceremony.

The awards ceremony will be presented virtually via Lunchpool.

Startup Day 2020

Discover the world-changing ideas coming from Knoxville’s entrepreneurs at Startup Day 2020! RSVP HERE!

Startup Day will be presented virtually using Knoxville based technology platform, Lunchpool.

Startup Day is an annual “Shark-Tank”-style pitch competition for a chance to win up to $10,000 in cash prizes. Six of Knoxville’s most investable startups will pitch their businesses in front of a panel of expert judges. In addition to the opportunity to spotlight their startup for investors, entrepreneurs will compete for a “crowd favorite” cash prize presented by BB&T and SunTrust Bank, now Truist.

Added to the Startup Day program this year is a special award and recognition of an inventor who has made a positive impact in the fight against COVID-19, presented by Verizon.

Join us for another great event of celebrating Knoxville’s robust entrepreneurial ecosystem!

Part 2: Q&A with Lia Winters of Winter Innovation

Startup Day 2019 winner reflects on the pitch competition experience, offers advice to 2020 competitors

Lia Winter has come a long way since she first developed the idea for a novel surgical stitching solution during her undergraduate days. Her East Tennessee-based startup is making waves at pitch competitions across the country, including right here in her backyard. Last year, Winter Innovations took home the Judge’s Choice and Crowd Favorite awards at the 2019 Startup Day pitch competition.

In this last-part of a two-part Q&A series with the Startup Day 2019 winner, Lia revisits last year’s win and offers some advice to the entrepreneurs vying for this year’s awards.

It’s been one year since you won the Judge’s Choice and Crowd Favorite awards at Startup Day 2019. What was the pitch competition experience like?

Lia: I attended Startup Day for the first time in 2018 and remember being impressed with the pitch competition finalists. It was a pleasant surprise when, just a year later, I received notification that Winter Innovations had been selected as a finalist for the 2019 Startup Day pitch competition. I started preparing my pitch deck immediately. WATE-TV news hosted the finalists for Elevator Pitch sessions, where the crew filmed us getting on an elevator with the news anchor and answering rapid fire questions about our companies. These segments were fun to shoot and they aired on the evening news a few weeks before Startup Day. 

After the Elevator Pitches, it was full speed ahead with pitch practice. I practiced a lot before my pitches and enlisted the help of my mentors at the Anderson Center for Entrepreneurship and Innovation to get feedback on my pitch. On the big day, we arrived early and did a practice run before it was show time. I was the first presenter and I actually felt very comfortable on stage, partly because the charismatic Brandon Bruce was the host, and partly because when I looked out into the crowd, I saw many familiar faces.

After we delivered our pitches and the judges deliberated, the Crowd Favorite prize was announced. I was so happy when they revealed the giant check and announced that we had won! We had done a lot to promote the event within our network. When the judges announced that we had also won the Judge’s Choice prize, I felt a mixture of elation and surprise because the other companies had delivered impressive presentations. The award money was put toward our first manufactured production batch of EasyWhip™ needles.

What advice can you give to the entrepreneurs competing this year? 

Lia: Part of the reason we were successful was because we told a story with our pitch. We shared our personal connection and passion for our company and the Knoxville area and its entrepreneurship support system. My advice to entrepreneurs competing this year would be to tell a story with your pitch and reflect on how the Knoxville ecosystem has helped your company grow.

Part 1: Q&A with Lia Winters of Winter Innovation

Winter Innovations continues to make strides one year after winning the Startup Day 2019 pitch competition

Lia Winter’s passion to revolutionize orthopedic surgery comes from firsthand experience. She suffered her own orthopedic injury in high school and witnessed her mother’s long road to recovery following complications from ACL surgery. Winter knew there had to be a way to improve the surgery process and she made it her goal to find it. The result? EasyWhipTM, a two-step surgical needle that improves the stability, speed, and efficiency of graft stitching. This device is the focus of Winter Innovations, founded in 2018.

Lia has successfully pitched her company in competitions around the country, including in East Tennessee. Winter Innovations took home the Judge’s Choice and Crowd Favorite awards at the 2019 Startup Day pitch competition

In this first-part of a two-part Q&A series with the Startup Day 2019 winner, Lia shares some exciting developments that have occurred over the last year.

A lot has happened for you and Winter Innovations this year. What are some notable highlights? 

Lia: The past year has been very exciting for Winter Innovations. Since competing in Startup Day, we’ve been featured in six other pitch competitions. In January, we closed our pre-seed funding round and are proud that our lead investor was an angel group from East Tennessee. We leveraged the capital to develop the EasyWhip™ packaging system and completed our first live production run of EasyWhip™ needles at our contract manufacturer last month. We also received a response from the U.S. Patent and Trademark Office concerning our primary patent application. We have a set of allowed claims that will protect EasyWhip™ in the marketplace and expect our first patent to issue soon. 

The pandemic has impacted people and companies around the world. How is Winter Innovations pivoting and/or adapting to this new world we live in? 

Lia: We’ve stayed focused on launching EasyWhip™. Elective surgeries for ligament and tendon repair have slowed in many areas of the country, but a surge is expected after the virus is under control. We are working diligently to complete the necessary testing to submit our 510(k) to the FDA so EasyWhip™ is ready for launch and can be available to help surgeons and patients when we do see an uptick in elective surgeries again. 

Our way of doing business has definitely changed, too. Things slowed down when the pandemic first hit, as many of our suppliers and manufacturers were faced with implementing social distancing measures and transitioning to shift work schedules. As a startup, we are used to adapting. We are busier than ever preparing for our FDA submission and have leveraged remote team members to support us in these efforts.

Looking ahead to the next year or two, what do you and Winter Innovations have on the horizon?

Lia: Our next significant milestone is to submit our 510(k) to the FDA, which we are on track to complete by the end of this year. We expect to obtain clearance and launch EasyWhip™ by the end of 2021. We are currently raising our seed funding round.

Competitors for Innov865 Week’s 2020 Startup Day Pitch Competition Announced

Six local startups will vie for $10,000 in cash prizes

KNOXVILLE, Tenn. – Some of the pitches shooting for $10,000 at Innov865’s Startup Day this year include predictive software for heart attacks, an untraceable password generator and glowing human cells to deliver medicine, among other ideas.

Those are among six rising stars from Knoxville’s startup scene that the Innov865 Alliance chose for its 2020 Startup Day pitch competition. The annual “Shark Tank”-style pitch competition is the premier event of Innov865 Week, which will be held virtually Sept. 28 – Oct. 2. Startup Day is at 2 p.m. Sept. 29. The event is free and open to the public.

Other pitches judges will hear include converting food into renewable electricity, a way to improve workplace safety through song, and a community-based certification system to champion youth fitness and education.

“Now, more than ever, it’s important to celebrate Knoxville’s vibrant entrepreneurial community,” said Jim Biggs, founding member of the Innov865 Alliance and Executive Director at the Knoxville Entrepreneur Center. “Innov865 Week shines a light on some of the incredible innovations that are happening in our own backyard. Any of these technologies could have an important impact on how we live.”

Hosted by the Innov865 Alliance, Innov865 Week spotlights Knoxville as a great place to start and grow businesses and connects the entrepreneurs planting roots here with support systems to succeed. The week’s events bring together local leaders, investors, entrepreneurs, and the public to support local economic development and celebrate Knoxville’s entrepreneurial spirit. 

The event will be presented virtually using the Knoxville-based technology platform, Lunchpool. Startup Day’s pitch competition will feature six of Knoxville’s most investable startups pitching their businesses in front of a panel of expert judges for a chance to win up to $10,000 in cash prizes. Two prizes are up for grabs: the Innov865 Judges’ Choice prize and the Innov865 Crowd Favorite prize, presented by BB&T and SunTrust Bank, now Truist.

A new addition to the 2020 Startup Day program is the Innov865 Impact Award, presented by Verizon. The Innov865 Impact Award recognizes an inventor who has made a positive impact in the fight against COVID-19. The inaugural Innov865 Impact Award recipient, along with the winners of the Innov865 Judges’ Choice and Innov865 Crowd Favorite prizes, will be announced at an awards ceremony that will be held at 11 a.m. Oct. 2. The awards ceremony will also be presented virtually via Lunchpool.

The six startups that will compete in Startup Day’s pitch competition were selected by the Innov865 Alliance for their extraordinary potential and investability. They include:

Electro-Active Technologies Inc. – Electro-Active Technologies Inc. is developing a modular system to convert food waste and renewable electricity into low-cost hydrogen. Their system keeps food waste out of landfills and provides a zero-emission fuel to offset gasoline and diesel use.

Cofounder and CEO: Alex Lewis

490 BioTech – 490 BioTech makes bioluminescent human cells capable of continuously producing a visual light signal that adjusts in real-time to represent changes in cellular health. The company’s glowing cells can be used by pharmaceutical companies in their efforts to develop safer, more effective, and less expensive medicines.

Cofounder and CSO: Dan Close

Quantum Lock – Quantum Lock is developing a smart lock system that is more secure than many current smartphone-based key systems. Quantum Lock’s technology uses quantum physics to generate keys that are random and untraceable.

Cofounder: Erica Grant

Qardian Labs – Qardian Labs develops innovative artificial intelligence-based software solutions for evaluating heart disease risk. The company is dedicated to reducing the occurrence of Sudden Cardiac Arrest by improving screening for people in high stress environments.

Founder: Sofia Tomov

PowerUp Fitness – PowerUp Fitness certifies wellness champions as youth fitness instructors and provides them with the training and support needed to empower youth through fitness, education, and fun in their communities.

Founder and CEO: Stacy Baugues

Songboarding – Songboarding is a subscription-based platform that combines music with safety training, providing employers with a fun and memorable alternative to traditional training methods.

Cofounder: Mike Benn

Learn more about Innov865 Week by visiting https://innov865week.com/. The events calendar will be updated as events are added throughout the week.

ABOUT INNOV865 WEEK AND THE INNOV865 ALLIANCE

Innov865 Week is a weeklong celebration of Knoxville’s entrepreneurial spirit that brings together startups, entrepreneurs, makers, investors, business leaders, students, and community leaders from across East Tennessee for a week of educational panels, pitch competitions, investor roundtables, and social events. It is presented by the Innov865 Alliance, a coalition that develops, supports, and promotes the region’s entrepreneurial ecosystem. The Innov865 Alliance’s mission is to make Knoxville a “nationally recognized” hub of innovation and entrepreneurship by leveraging the region’s world-class research, creative, and technological capabilities to build the most connected and diverse startup community in Tennessee. Founding members of the Innov865 Alliance include the University of Tennessee Research Foundation, Oak Ridge National Laboratory, PYA, UT’s Anderson Center for Entrepreneurship and Innovation, Three Roots Capital, Tennessee Valley Authority, Launch Tennessee, Knoxville Entrepreneur Center, UT Research Park at Cherokee Farm, and Bunker Labs Knoxville. To learn more, visit www.innov865.com/.